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  • Jetson Thor 🤖, Blue Origin orbital launch 🚀, SQLite fun facts 👨‍💻

    From TLDR@VERT to tldr@synchro.net on Tue Dec 31 11:33:30 2024
    --ThI5Th4A
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    Nvidia will be leaning more heavily into robotics in 2025. It will
    launch=
    a new generation of compact computers for humanoid robots
    called Jetson=

    Thor=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2= =A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C= =C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80= =8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0= =E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2= =A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=C2=A0=E2=80=8C=C2=A0= =E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2= =A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C= =C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80= =8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0= =E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2=A0=E2=80=8C=C2= =A0=E2=80=8C=C2=A0


    Sign Up [1] |Advertise [2]|View Online [3]=20
    =

    =09=09TLDR=20

    TLDR 2024-12-31

    =F0=9F=93=B1=20

    BIG TECH & STAR=
    TUPS

    NVIDIA'S NEXT MOVE: POWERING HUMANOID ROBOTS (1 MINUTE READ) [4]=
    =20

    Nvidia will be leaning more heavily into robotics in 2025. It will=

    launch a new generation of compact computers for humanoid robots
    calle=
    d Jetson Thor in the first half of next year. Nvidia aims to
    provide robo=
    t makers with an underlying OEM as its largest customers
    work to lessen t=
    heir dependence on the company's AI chips by
    developing their own.=20

    =
    BLUE ORIGIN INCHES CLOSER TO THE FIRST NEW GLENN FLIGHT (3 MINUTE
    READ) =
    [5]=20

    Blue Origin successfully performed a hotfire of its New Glenn ro=
    cket
    on December 27, the same day it was issued a commercial space launch=

    license from the US Federal Aviation Administration. The company
    remai=
    ns tightlipped about when it will launch its rocket, but it had
    claimed e=
    arlier in the year to be targeting a launch before the end of
    the year. N=
    ew Glenn was designed to be partly reusable. Its first
    stage, which is de=
    signed to be good for a minimum of 25 missions, will
    land on a downrange =
    sea-based platform.=20

    =F0=9F=9A=80=20

    SCIENCE & FUTURISTIC TECHNOLOG=
    Y

    CAUTIOUS OPTIMISM SURROUNDS PLANS FOR THE WORLD'S FIRST NUCLEAR
    F=
    USION POWER PLANT (3 MINUTE READ) [6]=20

    Commonwealth Fusion Systems ha=
    s announced plans to build the world's
    first nuclear fusion power plant. =
    The plant will be located in
    Chesterfield County, Virginia. If successful=
    , the plant will infuse
    400 megawatts power into the state's electrical g=
    rid starting in the
    early 2030s. Fusion technology still hasn't been prov=
    en to be viable -
    previous attempts by well-financed tech companies have =
    failed.=20

    WHY CHINA IS BUILDING A THORIUM MOLTEN-SALT REACTOR (4 MINUT=
    E READ)
    [7]=20

    China plans to start building a demonstration thorium-=
    based
    molten-salt reactor in the Gobi Desert next year. The 10-megawatt=

    reactor project is scheduled to be operational by 2030. Thorium-232 is=

    more abundant on Earth than uranium-235, but it isn't directly
    fissile=
    , so it must first be transformed into fissile uranium-233,
    which is tech=
    nically feasible, but it is unknown whether that is
    economical and practi=
    cal. If feasible, thorium, which is waste product
    of China's huge rare ea=
    rth mining industry, could reduce dependence on
    uranium.=20

    =
    =F0=9F=92=BB=20

    PROGRAMMING, DESIGN & DATA SCIENCE

    COLLECTION OF I=
    NSANE AND FUN FACTS ABOUT SQLITE (9 MINUTE READ) [8]=20

    SQLite is the m=
    ost deployed and used database. It is likely used more
    than all other dat=
    abases combined. SQLite is only maintained by three
    people who don't allo=
    w outside contributions. This blog post lists 24
    facts about the database=
    .=20

    WHAT IS A DEPENDENCY? (2 MINUTE READ) [9]=20

    A dependency cons=
    ists of a checksum, a location, a name, and a
    version. The checksum is a =
    cryptographic hash of the contents of the
    dependency. The location tells =
    systems how to acquire the dependency.
    The name tells when two different =
    dependencies correspond to different
    versions of the same thing. The vers=
    ion is a specific rule about
    dependency substitutability.=20

    =
    =F0=9F=8E=81=20

    MISCELLANEOUS

    GENETICALLY EDITED MOSQUITOES HAVEN'=
    T SCALED YET. WHY? (23 MINUTE
    READ) [10]=20

    Gene drives are a clever =
    genetic trick that forces a particular gene
    to be inherited by nearly all=
    offspring rather than the usual 50-50
    chance in normal inheritance. They=
    can propagate a desired mutation
    through an entire population theoretica=
    lly with only a few mating
    events. Some iterations of gene drives have be=
    en demonstrated to work
    in fruit flies, but mosquitoes are much more comp=
    licated and we don't
    fully understand them yet. This technology is also b=
    eing developed in
    countries where malaria is not endemic - the countries =
    that have
    problems with mosquitoes may not want to deal with the potentia=
    l
    ecological issues that may result from the use of gene drives.=20

    T=
    HE WEB IS TOO BIG, OR SCALING DOWN (10 MINUTE READ) [11]=20

    The modern =
    web is incredibly complex. WebAssembly made web technology
    the core of th=
    e future of computing. We are already using the browser
    as a replacement =
    for operating systems' graphics toolkits. Simplifying
    the web won't fix m=
    any of the widespread problems. There are a lot of
    smaller networks curre=
    ntly available that provide a look into what an
    alternative to the web mi=
    ght look like.=20

    =E2=9A=A1=20

    QUICK LINKS

    NVIDIA FINALIZES ACQ=
    UISITION OF AI SOFTWARE FIRM RUN:AI, TAKES
    SOFTWARE OPEN SOURCE =E2=80=
    =93 COMPANY REPORTEDLY COST $700 MILLION (3
    MINUTE READ) [12]=20

    Run:=
    ai offers GPU orchestration software that organizes groups of
    GPUs more e=
    fficiently.=20

    IF YOU DON'T LIKE SALES, DON'T START A COMPANY (1 MINUTE=
    READ) [13]=20

    Founders are always selling - sales is a skill that anyo=
    ne can get
    good at.=20

    ROBOTS ARE LEARNING TO CONDUCT SURGERY ON THEI=
    R OWN BY WATCHING
    VIDEOS (4 MINUTE READ) [14]=20

    Researchers from Joh=
    ns Hopkins University and Stanford University
    have trained robots to mani=
    pulate needles, tie knots, and suture
    wounds using video recordings of hu=
    man-controlled robotic arms
    performing surgical tasks.=20

    PASSKEY TEC=
    HNOLOGY IS ELEGANT, BUT IT'S MOST DEFINITELY NOT USABLE
    SECURITY (23 MINU=
    TE READ) [15]=20

    Passkeys were supposed to fix the problems with passwo=
    rds, but their
    inconsistent implementation has made them less practical t=
    han password
    managers.=20

    WRITING WRAPPED (14 MINUTE READ) [16]=20
    =

    A look over a year of writing by Anu Atluru, a founder and writer
    fro=
    m NYC.=20

    MONEY CAN BUY A LONGER LIFE=E2=80=94TO A POINT (4 MINUTE READ=
    ) [17]=20

    People with high salaries and net worth tend to live longer l=
    ives due
    to access to better healthcare, nutrition, and safer environment=
    s.=20

    Love TLDR? Tell your friends and get rewards!

    Share your ref=
    erral link below with friends to get free TLDR swag!=20

    https://refer.t=
    ldr.tech/1fd848fa/ [18]=20

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    executives, decision-makers and engineer=
    s, you may want to ADVERTISE
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    s or feedback, just respond to this email!=20

    Thanks for reading,=20
    Dan=
    Ni & Stephen Flanders=20

    If you don't want to receive future editions o=
    f TLDR, please
    unsubscribe from TLDR [21] or manage all of your TLDR news=
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    [5] https://www.theregister.com/202= 4/12/30/blue_origin_new_glenn_flight/?utm_source=3Dtldrnewsletter
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    --ThI5Th4A
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    <div style=3D"display: none; max-height: 0px; overflow: hidden;">Nvidia wil=
    l be leaning more heavily into robotics in 2025. It will launch a new gener= ation of compact computers for humanoid robots called Jetson Thor&nbsp;=E2= =80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2= =80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2= =80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2= =80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2= =80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2= =80=8C&nbsp;&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nb= sp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nb= sp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nb= sp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nb= sp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;=E2=80=8C&nb= sp;=E2=80=8C&nbsp;=E2=80=8C&nbsp;</div>




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    <table style=3D"table-layout: fixed; width:100%;" width=3D"100%"><tbody><tr= ><td style=3D"padding:0;border-collapse:collapse;border-spacing:0;margin:0;=

    <div style=3D"text-align: center;">

    <h1><strong>TLDR <span id=3D"date">2024-12-31</span></strong></h1>
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    <table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
    <div class=3D"text-block">
    <div style=3D"text-align: center;"><span style=3D"font-size: 36px;">=F0=9F= =93=B1</span></div></div>
    </td></tr></tbody></table>

    <table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
    <div class=3D"text-block">
    <div style=3D"text-align: center;">

    <h1><strong>Big Tech &amp; Startups</strong></h1>
    </div>
    </div>
    </td></tr></tbody></table>

    <table style=3D"table-layout: fixed; width: 100%;" width=3D"100%"><tbody><t= r><td style=3D"padding:0;border-collapse:collapse;border-spacing:0;margin:0=
    ;" valign=3D"top">

    <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px=

    <div class=3D"text-block">
    <span>
    <a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Ftechcrunch.com%2F2024%2F12%2F29%2Fnvidias-next-move-pow= ering-humanoid-robots%2F%3Futm_source=3Dtldrnewsletter/1/010001941c7e0ec7-8= 982f28e-cb0f-477d-ad32-75819383c7a4-000000/-e0AtsLa7TSvtvUb93pR0hxQi8JJdnA5= lyLWsmvJOjw=3D385">
    <span>
    <strong>Nvidia's next move: Powerin=
    g humanoid robots (1 minute read)</strong>
    </span>



    <span style=3D"font-family: &quot;Helvetica Neue&quot;, Helvetica, Arial, V= erdana, sans-serif;">
    Nvidia will be leaning more heavily int=
    o robotics in 2025. It will launch a new generation of compact computers fo=
    r humanoid robots called Jetson Thor in the first half of next year. Nvidia=
    aims to provide robot makers with an underlying OEM as its largest custome=
    rs work to lessen their dependence on the company's AI chips by developing = their own.
    </span>
    </span>
    </div>
    </td></tr></tbody></table>

    <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px=

    <div class=3D"text-block">
    <span>
    <a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fwww.theregister.com%2F2024%2F12%2F30%2Fblue_origin_new_= glenn_flight%2F%3Futm_source=3Dtldrnewsletter/1/010001941c7e0ec7-8982f28e-c= b0f-477d-ad32-75819383c7a4-000000/4kZWNpZK8iNf6IbdaCGkTkJpswx0FzDEmbcUVE1Fo= YY=3D385">
    <span>
    <strong>Blue Origin inches closer t=
    o the first New Glenn flight (3 minute read)</strong>
    </span>



    <span style=3D"font-family: &quot;Helvetica Neue&quot;, Helvetica, Arial, V= erdana, sans-serif;">
    Blue Origin successfully performed a ho= tfire of its New Glenn rocket on December 27, the same day it was issued a = commercial space launch license from the US Federal Aviation Administration=
    . The company remains tightlipped about when it will launch its rocket, but=
    it had claimed earlier in the year to be targeting a launch before the end=
    of the year. New Glenn was designed to be partly reusable. Its first stage=
    , which is designed to be good for a minimum of 25 missions, will land on a=
    downrange sea-based platform.
    </span>
    </span>
    </div>
    </td></tr></tbody></table>

    </td></tr></tbody></table>


    <table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
    <div class=3D"text-block">
    <div style=3D"text-align: center;"><span style=3D"font-size: 36px;">=F0=9F= =9A=80</span></div>
    </div>
    </td></tr></tbody></table>

    <table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
    <div class=3D"text-block">
    <div style=3D"text-align: center;">

    <h1><strong>Science &amp; Futuristic Technology</strong></h1>
    </div>
    </div>
    </td></tr></tbody></table>

    <table style=3D"table-layout: fixed; width: 100%;" width=3D"100%"><tbody><t= r><td style=3D"padding:0;border-collapse:collapse;border-spacing:0;margin:0=
    ;" valign=3D"top">

    <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px=

    <div class=3D"text-block">
    <span>
    <a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Ftheweek.com%2Fscience%2Fworld-first-fusion-power-plant%= 3Futm_source=3Dtldrnewsletter/1/010001941c7e0ec7-8982f28e-cb0f-477d-ad32-75= 819383c7a4-000000/bSRcAxSBKetz4reBj5Uxkq1ZSk8r0A-pgbpa45FMPKQ=3D385">
    <span>
    <strong>Cautious optimism surrounds=
    plans for the world's first nuclear fusion power plant (3 minute read)</st= rong>
    </span>



    <span style=3D"font-family: &quot;Helvetica Neue&quot;, Helvetica, Arial, V= erdana, sans-serif;">
    Commonwealth Fusion Systems has announc=
    ed plans to build the world's first nuclear fusion power plant. The plant w= ill be located in Chesterfield County, Virginia. If successful, the plant w= ill infuse 400 megawatts power into the state's electrical grid starting in=
    the early 2030s. Fusion technology still hasn't been proven to be viable -=
    previous attempts by well-financed tech companies have failed.
    </span>
    </span>
    </div>
    </td></tr></tbody></table>

    <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px=

    <div class=3D"text-block">
    <span>
    <a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fspectrum.ieee.org%2Fchinas-thorium-molten-salt-reactor%= 3Futm_source=3Dtldrnewsletter/1/010001941c7e0ec7-8982f28e-cb0f-477d-ad32-75= 819383c7a4-000000/hEdW7YsiXbUXuSPKNWxnbOA_YYno_wOEthfJ6ZAcEzk=3D385">
    <span>
    <strong>Why China Is Building a Tho= rium Molten-Salt Reactor (4 minute read)</strong>
    </span>



    <span style=3D"font-family: &quot;Helvetica Neue&quot;, Helvetica, Arial, V= erdana, sans-serif;">
    China plans to start building a demonst= ration thorium-based molten-salt reactor in the Gobi Desert next year. The = 10-megawatt reactor project is scheduled to be operational by 2030. Thorium= -232 is more abundant on Earth than uranium-235, but it isn't directly fiss= ile, so it must first be transformed into fissile uranium-233, which is tec= hnically feasible, but it is unknown whether that is economical and practic= al. If feasible, thorium, which is waste product of China's huge rare earth=
    mining industry, could reduce dependence on uranium.
    </span>
    </span>
    </div>
    </td></tr></tbody></table>

    </td></tr></tbody></table>


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    <div class=3D"text-block">
    <div style=3D"text-align: center;"><span style=3D"font-size: 36px;">=F0=9F= =92=BB</span></div></div>
    </td></tr></tbody></table>

    <table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
    <div class=3D"text-block">
    <div style=3D"text-align: center;">

    <h1><strong>Programming, Design &amp; Data Science</strong></h1>
    </div>
    </div>
    </td></tr></tbody></table>

    <table style=3D"table-layout: fixed; width: 100%;" width=3D"100%"><tbody><t= r><td style=3D"padding:0;border-collapse:collapse;border-spacing:0;margin:0=
    ;" valign=3D"top">

    <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px=

    <div class=3D"text-block">
    <span>
    <a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Favi.im%2Fblag%2F2024%2Fsqlite-facts%2F%3Futm_source=3Dt= ldrnewsletter/1/010001941c7e0ec7-8982f28e-cb0f-477d-ad32-75819383c7a4-00000= 0/RRCSE3Z62HtPj1AlxCk5-EZwUwjOH4DmZK9RbmQk0ps=3D385">
    <span>
    <strong>Collection of insane and fu=
    n facts about SQLite (9 minute read)</strong>
    </span>



    <span style=3D"font-family: &quot;Helvetica Neue&quot;, Helvetica, Arial, V= erdana, sans-serif;">
    SQLite is the most deployed and used da= tabase. It is likely used more than all other databases combined. SQLite is=
    only maintained by three people who don't allow outside contributions. Thi=
    s blog post lists 24 facts about the database.
    </span>
    </span>
    </div>
    </td></tr></tbody></table>

    <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px=

    <div class=3D"text-block">
    <span>
    <a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fmatklad.github.io%2F2024%2F12%2F30%2Fwhat-is-dependency= .html%3Futm_source=3Dtldrnewsletter/1/010001941c7e0ec7-8982f28e-cb0f-477d-a= d32-75819383c7a4-000000/d69BUBWVS408df2_L8zrOn3urVaOQlV5fnSsgA75gE0=3D385">
    <span>
    <strong>What is a dependency? (2 mi= nute read)</strong>
    </span>



    <span style=3D"font-family: &quot;Helvetica Neue&quot;, Helvetica, Arial, V= erdana, sans-serif;">
    A dependency consists of a checksum, a = location, a name, and a version. The checksum is a cryptographic hash of th=
    e contents of the dependency. The location tells systems how to acquire the=
    dependency. The name tells when two different dependencies correspond to d= ifferent versions of the same thing. The version is a specific rule about d= ependency substitutability.
    </span>
    </span>
    </div>
    </td></tr></tbody></table>

    </td></tr></tbody></table>



    <table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
    <div class=3D"text-block">
    <div style=3D"text-align: center;"><span style=3D"font-size: 36px;">=F0=9F= =8E=81</span></div></div>
    </td></tr></tbody></table>

    <table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
    <div class=3D"text-block">
    <div style=3D"text-align: center;"><strong><h1>Miscellaneous</h1></strong><= /div>
    </div>
    </td></tr></tbody></table>

    <table bgcolor=3D"" style=3D"table-layout: fixed; width: 100%;" width=3D"10= 0%"><tbody><tr><td style=3D"padding:0;border-collapse:collapse;border-spaci= ng:0;margin:0;" valign=3D"top">

    <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px=

    <div class=3D"text-block">
    <span>
    <a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Feryney.substack.com%2Fp%2Fgenetically-edited-mosquitoes= -havent%3Futm_source=3Dtldrnewsletter/1/010001941c7e0ec7-8982f28e-cb0f-477d= -ad32-75819383c7a4-000000/tVs0oPA-_N-tDweAsTb_M-gBo8ckFrwCu6XWhp0cE48=3D385=

    <span>
    <strong>Genetically edited mosquito=
    es haven't scaled yet. Why? (23 minute read)</strong>
    </span>



    <span style=3D"font-family: &quot;Helvetica Neue&quot;, Helvetica, Arial, V= erdana, sans-serif;">
    Gene drives are a clever genetic trick = that forces a particular gene to be inherited by nearly all offspring rathe=
    r than the usual 50-50 chance in normal inheritance. They can propagate a d= esired mutation through an entire population theoretically with only a few = mating events. Some iterations of gene drives have been demonstrated to wor=
    k in fruit flies, but mosquitoes are much more complicated and we don't ful=
    ly understand them yet. This technology is also being developed in countrie=
    s where malaria is not endemic - the countries that have problems with mosq= uitoes may not want to deal with the potential ecological issues that may r= esult from the use of gene drives.
    </span>
    </span>
    </div>
    </td></tr></tbody></table>

    <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px=

    <div class=3D"text-block">
    <span>
    <a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fscottrichmond.me%2Fthe-web-is-too-big%2F%3Futm_source= =3Dtldrnewsletter/1/010001941c7e0ec7-8982f28e-cb0f-477d-ad32-75819383c7a4-0= 00000/Hc62wvjiOlKvoQ3ibP_HBYbMrxUJudLhf6Ph_DzLiAQ=3D385">
    <span>
    <strong>The web is too big, or scal= ing down (10 minute read)</strong>
    </span>



    <span style=3D"font-family: &quot;Helvetica Neue&quot;, Helvetica, Arial, V= erdana, sans-serif;">
    The modern web is incredibly complex. W= ebAssembly made web technology the core of the future of computing. We are = already using the browser as a replacement for operating systems' graphics = toolkits. Simplifying the web won't fix many of the widespread problems. Th= ere are a lot of smaller networks currently available that provide a look i= nto what an alternative to the web might look like.
    </span>
    </span>
    </div>
    </td></tr></tbody></table>

    </td></tr></tbody></table>


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    <div class=3D"text-block">
    <div style=3D"text-align: center;"><span style=3D"font-size: 36px;">=E2=9A= =A1</span></div></div>
    </td></tr></tbody></table>

    <table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
    <div class=3D"text-block">
    <div style=3D"text-align: center;">

    <h1><strong>Quick Links</strong></h1>
    </div>
    </div>
    </td></tr></tbody></table>

    <table bgcolor=3D"" style=3D"table-layout: fixed; width: 100%;" width=3D"10= 0%"><tbody><tr><td style=3D"padding:0;border-collapse:collapse;border-spaci= ng:0;margin:0;" valign=3D"top">

    <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px=

    <div class=3D"text-block">
    <span>
    <a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fwww.tomshardware.com%2Ftech-industry%2Fartificial-intel= ligence%2Fnvidia-finalizes-acquisition-of-ai-software-firm-run-ai-takes-sof= tware-open-source-company-reportedly-cost-usd700-million%3Futm_source=3Dtld= rnewsletter/1/010001941c7e0ec7-8982f28e-cb0f-477d-ad32-75819383c7a4-000000/= B6rcIrhHvJ1a5TqoB_AxaXhAv_DfJNFzpco7CV9Im2g=3D385">
    <span>
    <strong>Nvidia finalizes acquisitio=
    n of AI software firm Run:ai, takes software open source =E2=80=93 company = reportedly cost $700 million (3 minute read)</strong>
    </span>



    <span style=3D"font-family: &quot;Helvetica Neue&quot;, Helvetica, Arial, V= erdana, sans-serif;">
    Run:ai offers GPU orchestration softwar=
    e that organizes groups of GPUs more efficiently.
    </span>
    </span>
    </div>
    </td></tr></tbody></table>

    <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px=

    <div class=3D"text-block">
    <span>
    <a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fhunterwalk.com%2F2024%2F12%2F30%2Fif-you-dont-like-sale= s-dont-start-a-company%2F%3Futm_source=3Dtldrnewsletter/1/010001941c7e0ec7-= 8982f28e-cb0f-477d-ad32-75819383c7a4-000000/b7kAHR-TAB0QvX3_B_QqEBU-f_lcOOF= ZJJ79HBVA03k=3D385">
    <span>
    <strong>If You Don't Like Sales, Do= n't Start a Company (1 minute read)</strong>
    </span>



    <span style=3D"font-family: &quot;Helvetica Neue&quot;, Helvetica, Arial, V= erdana, sans-serif;">
    Founders are always selling - sales is =
    a skill that anyone can get good at.
    </span>
    </span>
    </div>
    </td></tr></tbody></table>

    <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px=

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